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TTC - The Great Courses - Biology The Science of Life [Course No 1500]

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TTC - The Great Courses - Biology The
Science of Life [Course No. 1500]
Professor Stephen Nowicki, Ph.D.
Duke University 





One of the greatest scientific feats of our era is the astonishing progress made in understanding the
intricate machinery of life. We are living in the most productive phase so far in this quest, as researchers delve ever
deeper into the workings of living systems, turning their discoveries into new medical treatments, improved methods of
growing food, and innovative new products.

"The 21st century will be the century of biological science,
just as the 20th century was the century of physical science," predicts Professor Stephen Nowicki, an award-winning
teacher at Duke University who has specially adapted his acclaimed introductory biology course for The Teaching Company
to bring you up to date on one of the most important fields of knowledge of our time.

This intensive,
72-lecture course will give you the background and guidance to explore in depth the fundamental principles of how living
things work—principles such as evolution by natural selection, the cellular structure of organisms, the DNA
theory of inheritance, and other key ideas that will help you appreciate the marvelous diversity and complexity of
life.

Explore Living Systems at All Levels

Make no mistake: This is a challenging course. But the
rewards are tremendous. You will explore living systems at all levels, from biological molecules to global ecosystems.
Along the way, you will gain insight into some of the most pressing questions facing society:

    What does
it mean to say that the human genome has been sequenced, and why should we sequence the genomes of other species?
 
  How is an organism genetically modified or cloned, and what are the benefits—or potential costs—of doing
so?
    What are stem cells, and how might they contribute to health and welfare?
    Why is HIV/AIDS so
difficult to treat?
    What will happen if vast tracts of tropical rainforest are cut down, and why does it matter
that the temperature of the Earth is rising? 

In addition, you will discover the mechanisms behind such
intriguing phenomena as why children resemble their parents, what causes plants to bend toward light, how memories are
stored, why some birds have very long tails, and how life itself began on Earth.

Above all, you will learn
how to think about biology, so that in your day-to-day life you will understand the significance and complexities of
news stories, medical issues, and public debates, not to mention what is going on in your own garden and in nature all
around you.

The Unifying Themes of Biology

Professor Nowicki presents the subject in a conceptual
format, emphasizing the importance of broad principles. Facts and details are offered in abundance, but in the context
of developing a framework that listeners can absorb.

The course is organized around three unifying themes:

    Starting with "Information and Evolution" (Lectures 1-24), you investigate how information about
the structure and organization of living things is found in the DNA molecule, how this information is transmitted and
modified, and the implications of these processes for understanding life. One important conclusion of this discussion is
that species inevitably change over time; that is, that life evolves.
    In "Development and
Homeostasis" (Lectures 25-48), you consider two related issues for understanding the workings of complex organisms:
how single cells (fertilized eggs) proliferate and transform into complex, multicellular organisms, and how parts of
complex organisms remain coordinated and maintain their integrity in the face of different challenges.
    In
"Energy and Resources" (Lectures 49-72), you learn how living systems obtain the energy and other materials
needed to maintain their highly ordered state and the implications of these processes for understanding the organization
of biology at all levels of scale. Ultimately this investigation leads into the discipline of ecology and to
considerations of energy and resource limitations for the entire planet.

The Great Experiments of Biology

One of the distinctive features of this course is that you learn much of the material through the great
experiments that revealed new and unexpected aspects of the living world to science, including:

    Gregor
Mendel discovered the fundamental principles of inheritance through his work on trait transmission in garden peas in the
mid-1800s
    Thomas Hunt Morgan introduced the fruit fly as a model system for modern genetics in the early 20th
century. Morgan's work and that of his many students demonstrated that genes occur on chromosomes.
    Konrad
Lorenz's mid-20th-century work on releasers and fixed action patterns in the behavior of greylag geese and other
animals helped establish the modern study of animal behavior.
    Arthur Kornberg's discovery of DNA
polymerase in 1958 helped spark today's revolution in biotechnology and genetic engineering.

In your
systematic study of biology under Professor Nowicki's guidance, you will encounter a wealth of interesting
information and observations, such as:

    Some cells in a developing organism are preprogrammed to die, a
process that is important, for example, in creating the spaces between our fingers and toes.
    The accumulation
of oxygen in Earth's atmosphere following the evolution of photosynthetic bacteria was a disaster of global
proportions for most of the organisms that lived before oxygen appeared on the planet.
    The ability of cells to
recognize self from non-self is widespread in animals, even among creatures as simple as sponges. If you take two
sponges of the same species and dissociate their cells, then mix those cells, the cells will reassociate with the
individual they came from.
    Some species of moths and butterflies develop into different looking caterpillars or
adults depending on the time of year that they happen to be born. It is the available food source that turns the
caterpillar into one form or another. 

The diversity of life is indeed remarkable—and so will be your
experience with this course. You may not understand everything the first or even the second time you hear it, but
"the point isn't to remember the details," says Professor Nowicki. "The point is to understand how
the details are processed, how they're analyzed, how biologists come up with these ideas, and how to think about
the new information you might encounter in the future.

"My goal in teaching is to have somebody able to
open up a newspaper and say, 'I understand why this is an important discovery in biology.'"

https://www.thegreatcourses.com/courses/biology-the-science-of-life.html

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